Alcoholism: Physical dependence on alcohol to the extent that stopping alcohol use will bring on withdrawal symptoms. In popular and therapeutic parlance, the term may also be used to refer to ingrained drinking habits that cause health or social problems. Treatment requires first ending the physical dependence, then making lifestyle changes that help the individual avoid relapse. In some cases, medication or hospitalization are needed. Alcohol dependence can have many serious effects on the brain, liver, and other organs of the body.